Types and cleavage methods of ADC linker
At present, common linkers can be mainly divided into two categories according to the cleavage method: chemical cleavage and enzymatic cleavage. 1. Chemical cracking linker
At present, common linkers can be mainly divided into two categories according to the cleavage method: chemical cleavage and enzymatic cleavage. 1. Chemical cracking linker
ADC drugs refer to monoclonal antibodies linked by covalent linkers and cytotoxic small molecule payloads to achieve targeted drug delivery. ADC drug targeted therapy mechanism1: