Composition of antibody-drug conjugate
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December 13, 2022
An antibody-drug conjugate (ADC) is a type of biopharmaceutical drug that is composed of an antibody and a cytotoxic drug. The purpose of an ADC
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Principle of ADC conjugation technology
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December 10, 2022
ADC, or antibody-drug conjugate, is a type of drug that combPrinciple ofines an antibody with a toxic drug in order to specifically target and kill
Pfizer and BioNTech countersued Moderna over COVID-19 vaccine technology patents
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December 8, 2022
Recently, Pfizer of the United States and its German partner BioNTech countersued rival Moderna for the patent of the COVID-19 vaccine technology. broad” and “unenforceable”.
FDA approves first fecal microbe therapy
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December 2, 2022
On November 30, 2022, Ferring Pharmaceuticals announced that its microbiome therapy REBYOTA® (RBX2660) was approved by the FDA, becoming the first approved fecal microbial therapy.
Clinical evaluation of new CAR-T therapy
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November 30, 2022
In recent years, chimeric antigen receptor (CAR) T-cell therapy for hematological malignancies has become a major breakthrough in cell therapy. To date, the U.S. Food
Mechanism of action of antibody-drug conjugates
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November 25, 2022
Antibody-drug conjugates (ADCs) have achieved remarkable efficacy in cancer treatment and have attracted worldwide attention. Although ADCs pose significant challenges to researchers, especially in identifying
The future of drugs targeting MYC
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November 22, 2022
The transcription factor family consists of c-MYC, L-MYC and N-MYC, which are the main regulators of cellular processes such as cell proliferation, cell differentiation, cell
Importance of protein-polymer coupling
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November 16, 2022
Protein-polymer conjugates are widely used as disease therapeutics and have advantages such as high target specificity. but their use also faces some challenges: rapid clearance
What is vaccine adjuvant?
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November 12, 2022
We are not unfamiliar with vaccines, but few people know about vaccine adjuvants. The so-called adjuvant refers to the substance added to the vaccine that
ADCC targeting mechanism of CD16a
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November 12, 2022
Antibody-dependent cell-mediated cytotoxicity (ADCC) is a potent mechanism of cytotoxicity, mainly mediated by natural killer (NK) cells. When specific antibodies bind to the targeted cell
Classification and application of tumor markers
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November 11, 2022
Tumor markers (TM) refer to the synthesis and secretion of tumor cells and gene expression during the occurrence and proliferation of malignant tumors, or the
AstraZeneca abandons U.S. application for COVID-19 vaccine, halts development of multiple drugs
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November 11, 2022
On November 10, when AstraZeneca announced its third-quarter 2022 results, it also announced that it would not submit a listing application for the new crown
